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Aging and the microbiome: implications for health and disease
WenTing Gao1, Hye-Yeon Lee1, Kyung-Jin Min1
1Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Korea.
BMB Reports
|November 23, 2025
Summary
The aging gut microbiota drives age-related decline and diseases. Interventions like probiotics may help restore microbial balance and promote healthy aging.
Area of Science:
- Microbiology
- Gerontology
- Immunology
Background:
- The gut microbiota is crucial for host homeostasis.
- Aging significantly alters gut microbiota composition and function.
- Microbiota changes are drivers, not just consequences, of aging.
Conclusions:
- Gut microbiota alterations are key drivers of aging and associated diseases.
- Microbiota-targeted interventions (probiotics, prebiotics, postbiotics) show therapeutic potential.
- Further research into advanced strategies is warranted for healthy aging.
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