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Psychometric Properties of the SarQoL Questionnaire: A Systematic Review and Meta-Analysis
Céline Demonceau1, Brabant Christian1, Shukuru Emmanuel2
1Research Unit in Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
Journal of Cachexia, Sarcopenia and Muscle
|November 23, 2025
Summary
This study confirms the Sarcopenia and Quality of Life (SarQoL) questionnaire has strong reliability, validity, and responsiveness. The findings support SarQoL as a dependable tool for assessing health-related quality of life in older adults with sarcopenia.
Area of Science:
- Gerontology
- Clinical Psychology
- Health Outcomes Research
Background:
- The Sarcopenia and Quality of Life (SarQoL) questionnaire is the sole disease-specific patient-reported outcome measure (PROM) for sarcopenia-related health-related quality of life (HRQoL).
- Assessing the psychometric properties of SarQoL is crucial for its reliable application in clinical practice and research.
Purpose of the Study:
- To systematically review and quantitatively summarize evidence on the reliability, validity, responsiveness, and floor/ceiling effects of the SarQoL questionnaire.
- To evaluate the SarQoL's performance in older adults using a consensual definition of sarcopenia.
Main Methods:
- A systematic literature search was conducted following PRISMA-COSMIN guidelines across MEDLINE, PsycINFO, Scopus, and EMBASE.
- Studies published between 2013 and November 2024 evaluating SarQoL's psychometric properties in older adults were included.
- A random-effects model meta-analysis was employed for data synthesis.
Main Results:
- Twenty-five studies involving 4585 individuals (1311 with sarcopenia) met the inclusion criteria.
- SarQoL demonstrated high reliability (Cronbach's alpha > 0.80) and excellent test-retest reliability (ICC = 0.98).
- Strong construct validity was confirmed, and responsiveness was supported, with high certainty of evidence for all properties.
Conclusions:
- This meta-analysis provides robust evidence for the strong psychometric properties of the SarQoL questionnaire.
- The findings consolidate a decade of research, affirming SarQoL's utility in measuring HRQoL in older adults with sarcopenia.
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