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Risk factors for coagulase-negative staphylococcal surgical site infections

Cynthia Nguyen1, Amanda Brown1, Alison Lew1

  • 1https://ror.org/0076kfe04The University of Chicago Medicine, USA.

Epidemiology and Infection
|November 24, 2025
PubMed

Insights

This study identified risk factors for coagulase-negative staphylococcal (CoNS) surgical site infections (SSI). Male sex and respiratory conditions like asthma or COPD increase CoNS SSI risk, while colon surgery may reduce it.

Area of Science:

  • Infectious Diseases
  • Surgical Outcomes
  • Microbiology

Background:

  • Surgical site infections (SSI) pose a significant threat to patient recovery.
  • Coagulase-negative staphylococci (CoNS) are common pathogens in SSIs.
  • Identifying specific risk factors for CoNS SSI is crucial for prevention.

Purpose of the Study:

  • To determine the risk factors associated with CoNS SSI.
  • To inform targeted prevention strategies for CoNS SSIs.

Main Methods:

  • Retrospective analysis of patient data.
  • Statistical evaluation to identify significant risk factors.

Main Results:

  • Male sex was identified as a risk factor for CoNS SSI.
  • Asthma and Chronic Obstructive Pulmonary Disease (COPD) were associated with increased CoNS SSI risk.
  • Colon surgery demonstrated a reduced risk of CoNS SSI.

Conclusions:

  • Specific patient demographics and comorbidities are linked to CoNS SSI.
  • Surgical site selection may influence the risk of CoNS SSI.
  • Further research can optimize CoNS SSI prevention protocols.
Keywords:
methicillin resistantprophylaxisstaphylococcussurgical site infectionvancomycin

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