Related Experiment Video
Updated: Jan 10, 2026

Clinical Practice Protocol of Creative Music Therapy for Preterm Infants and Their Parents in the Neonatal Intensive Care Unit
Published on: January 7, 2020
[Exploring the Effects of Cycled Lighting on Sleep Patterns in Premature Infants During Hospitalization]
Jia-Hua Li1, Hsiang-Yun Lan2, Jen-Jiuan Liaw2
1Department of Nursing, MacKay Memorial Hospital, Taiwan, ROC.
Insights
Cyclic lighting significantly improved sleep duration and efficiency in premature infants hospitalized in the NICU. This intervention enhances sleep quality, supporting infant development and care.
Area of Science:
- Neonatal care
- Sleep science
- Developmental pediatrics
Background:
- Sleep is crucial for brain maturation and development, especially in premature infants.
- Sleep is often disturbed in premature infants during NICU hospitalization.
- Interventions to improve sleep quality in this population are under-researched.
Purpose of the Study:
- To investigate the effect of cyclic light exposure on the sleep quality of hospitalized premature infants.
- To assess if controlled lighting conditions can mitigate sleep disturbances in vulnerable newborns.
Main Methods:
- A randomized controlled trial with 68 premature infants (28-36 weeks gestation) was conducted.
- The intervention group received cyclic lighting from 32 weeks gestation; the control group received standard care.
- Sleep was measured using actigraphy at pre-test and post-test, with data analyzed using generalized estimating equations.
Main Results:
- The cyclic lighting group showed a significantly greater increase in total nighttime sleep duration compared to the control group (p = .031).
- Nighttime sleep efficiency improved significantly more in the intervention group (8.92%, p = .032) than in the control group.
- These findings indicate a positive impact of cyclic lighting on key sleep parameters.
Conclusions:
- Cyclic lighting effectively enhances total nighttime sleep duration and sleep efficiency in premature infants.
- This intervention improves sleep quality during hospitalization, supporting infant development.
- Healthcare providers are encouraged to implement cyclic lighting to optimize sleep care for hospitalized premature infants.
Background:
Sleep, a fundamental human need and the primary behavioral state of newborns, plays a critical role in brain maturation and development and, in particular, influences the growth of premature infants. However, sleep in premature infants is frequently disturbed and interrupted during their stay in intensive care units, and interventions designed to improve sleep quality during hospitalization have been inadequately investigated.
Purpose:
This study was designed to examine the impact of cyclic light exposure on sleep quality in premature infants during hospitalization.
Methods:
This randomized controlled trial was conducted using a repeated measures design on a sample of 68 premature infants born between 28 to 36 weeks of gestation. The experimental group was exposed to cyclic lighting starting at 32 weeks of gestation during their NICU stay, while the control group received standard care. The sleep data were collected using actigraphy, with measurements taken at two time points: pre-intervention (pre-test) and immediately prior to discharge (post-test). Data analysis was conducted using generalized estimating equations.
Results:
The intervention group reported a significantly greater pre-test / post-test increase in terms of total nighttime sleep duration than the control group (B = 64.52, p = .031). Moreover, the improvement in nighttime sleep efficiency between the two time points in the intervention group (8.92%, p = .032) was significantly greater than in the control group.
Conclusions / Implications For Practice:
The findings suggest cyclic lighting enhances both total nighttime sleep duration and sleep efficiency in premature infants, improving sleep quality during hospitalization. These results informs clinical practice through encouraging healthcare providers to prioritize sleep care for hospitalized premature infants. Implementing cyclic lighting may support the development of more-optimal sleep cycles in premature infants, fostering overall infant development and improving quality of care.
Related Concept Videos
Management of Insomnia
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...

