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Updated: Jan 10, 2026

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
Development and applications of heterogeneous chiral bifunctional alkaloid-thioureas as recyclable organocatalysts
Ainara Pellicer1,2, Xabier Del Corte1, Nora Aranburu3
1Department of Organic Chemistry I, Faculty of Pharmacy, University of the Basque Country UPV/EHU, Paseo de la Universidad 7, 01006 Vitoria-Gasteiz, Spain. aitor.maestro@ehu.eus.
Abstract:
The development of heterogeneous chiral catalysts is a growing research field, offering recyclable alternatives to their homogeneous counterparts. With the aim of identifying a general and reliable methodology to access highly recyclable catalysts, herein, a structure-activity relationship study of chiral base-thiourea bifunctional catalysts is reported. The solid-supported catalysts have been benchmarked using well-known model reactions, allowing recycling of the catalyst up to 15 times without a decrease in the chiral induction properties.
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