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Related Experiment Video

Updated: Jan 10, 2026

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Acute Care Use Among People With Sickle Cell Disease, Sickle Cell Data Collection Program, 8 US States, 2018.

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  • 1Division of Population Health Data, Office of Family Health Services, Virginia Department of Health, Richmond, VA, USA.

Public Health Reports (Washington, D.C. : 1974)
|November 24, 2025
PubMed
Summary

Hospital admissions and emergency department (ED) visits are common for sickle cell disease patients. Most acute care episodes, including hospital admissions, begin in the ED, highlighting the need for improved outpatient management.

Keywords:
acute care useemergency department visitshealth care disparitiespublic health insurancesickle cell disease

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Area of Science:

  • Hematology
  • Public Health
  • Health Services Research

Background:

  • Sickle cell disease (SCD) management requires understanding acute care utilization patterns.
  • Improving care access for SCD patients necessitates analyzing hospital admission and emergency department (ED) visit trends.

Purpose of the Study:

  • To characterize acute care use among individuals with SCD.
  • To identify patterns in acute care utilization across different age groups and sexes.
  • To analyze 2018 data on hospital admissions and ED visits for SCD patients.

Main Methods:

  • Cross-sectional study utilizing population-based data from 8 states in the CDC's Sickle Cell Data Collection program.
  • Analysis of data from 27,034 individuals with confirmed or probable SCD diagnosis in 2018.
  • Examination of hospital admissions, ED treat-and-release (T/R) visits, and readmissions.

Main Results:

  • In 2018, 40.2% of the SCD cohort experienced at least one hospital admission, and 57.0% had at least one ED T/R visit.
  • Out of 98,617 acute care encounters, 93.6% involved the ED.
  • The majority of hospital admissions for SCD patients were initiated in the ED.

Conclusions:

  • Hospital admissions are frequent among individuals with SCD, affecting less than half of the population studied.
  • Over half of the SCD population utilized ED services, with most hospitalizations originating from the ED.
  • Further research is needed to understand variations in acute care use, high ED T/R rates, and outpatient treatment strategies for SCD.