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Nascent CUT&Tag captures transcription factor binding after chromatin duplication

Matthew Wooten, Kevin Nguyen, Brittany N Takushi

    Biorxiv : the Preprint Server for Biology
    |November 24, 2025
    PubMed
    Summary

    Chromatin proteins are displaced during DNA replication and must reassemble. Nascent CUT&Tag tracks GAGA factor (GAF) recovery on new DNA, revealing distinct early and late binding patterns linked to cell cycle and development.

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