Related Experiment Video
Updated: Jan 10, 2026

Author Spotlight: Coproparasitoscopic Examination of Dog Stools for Control and Prevention of Zoonotic Parasite Diseases
Published on: December 15, 2023
Fluke-borne viruses are a risk factor for diseases caused by carcinogenic trematodes
Sujittra Chaiyadet1,2, Tom Roblin3, Anais Fauchois4,5
1Department of Tropical Medicine, Faculty of Medicine, Khon Kaen University; Khon Kaen 40002, Thailand.
Abstract:
Three trematode parasites, Schistosoma haematobium, Opisthorchis viverrini and Clonorchis sinensis are recognized group 1 biological carcinogens. Herein, we showed that all three carcinogenic trematodes harbor viruses. Focusing on O. viverrini, we determined virus persistence at discrete life stages, viral tropism for the fluke tegument, and provided molecular and serological evidence of virus transmission to parasitized hamsters. Serological analyses confirmed seroconversion of O. viverrini-infected residents in endemic regions. We observed that antibody titer and avidity against fluke viruses increase in infected individuals with hepatobiliary diseases. Using random forest, we showed that fluke virus serologies discriminate efficiently between liver-fluke infected participants without disease from those with periductal fibrosis or cholangiocarcinoma. Altogether, this discovery shows that fluke-borne viruses are a risk factor and diagnostic target for fluke-associated cancer.
More Related Videos
09:27A Rapid Strategy for the Isolation of New Faustoviruses from Environmental Samples Using Vermamoeba vermiformis
Published on: June 4, 2016
06:02Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
Published on: September 13, 2018
Related Concept Videos
Mechanisms of Retrovirus-induced Cancers
Diversity of Protists II
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Viral Recombination
Cancer Prevention
Some...
Bacterial Phylum Spirochaetes