Related Experiment Video

Updated: Jan 10, 2026

Mutagenesis and Functional Analysis of Ion Channels Heterologously Expressed in Mammalian Cells
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Mutagenesis and Functional Analysis of Ion Channels Heterologously Expressed in Mammalian Cells

Published on: October 1, 2010

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Functionally-Coupled Ion Channels Begin Co-assembling at the Start of Their Synthesis

Roya Pournejati, Jessica M Huang, Michael Ma

    Biorxiv : the Preprint Server for Biology
    |November 24, 2025
    PubMed
    Summary

    BK and Ca V1.3 channels form complexes before reaching the cell membrane. This pre-assembly in the endoplasmic reticulum and Golgi explains their functional coupling and proximity in cellular structures.

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