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Intravenous Administration of Serotonergic Psychedelics Produce Short-lasting Changes in Sleep-Wake Behavior and High

Nicholas Kolbman, Emma R Huels, Amanda Nelson

    Biorxiv : the Preprint Server for Biology
    |November 24, 2025
    PubMed
    Summary

    Psychedelics like psilocybin and DMT minimally affect sleep-wake states but alter EEG spectral power and functional connectivity, particularly in the high gamma band during wakefulness and sleep.

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