Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Posterior Segment Pressurization With Intravitreal Balanced Salt Solution to Stabilize Anterior Chamber Gas During Endothelial Keratoplasty.

Cornea·2026

Same author

Keratitis patterns in patients with human immunodeficiency virus: A 10-year retrospective study.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society·2026

Same author

<i>Nocardia</i> keratitis: Microbiological characteristics, antibiotic sensitivity, and clinical profile in a tertiary care setting.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society·2026

Same author

Predictors of retinal detachment and visual outcome in acute retinal necrosis: a 14-year retrospective cohort.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026

Same author

Beyond diagnosis: AI-based surgical risk assessment in Acanthamoeba keratitis with real-world validation.

The ocular surface·2026

Same author

Demographic, surgical, and radiologic determinants of patient-reported outcomes, hospitalization, and return to work after acetabular fracture ORIF: a tertiary trauma center experience with a minimum two-year follow-up.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2026

Same journal

A Biologically Dominant Trophoblastic Component Guiding Neoadjuvant EMA/CO in Endometrial Carcinoma: A Clinical Case Report.

Clinical case reports·2026

Same journal

Could Fabry Disease Cause Giant Coronary Aneurysms in a 7-Month-Old Infant: A Case Report.

Clinical case reports·2026

Same journal

Correction to "Loss of Consciousness in a Child Following Accidental Ingestion of Brimonidine Ointment: A Case Report".

Clinical case reports·2026

Same journal

Simultaneous Transvenous Lead Extraction and Intra-Operative Epicardial Extravascular Defibrillator (EV-ICD) Implantation During Tricuspid Valve Replacement.

Clinical case reports·2026

Same journal

Successful Surgical Management of Chronic Subdural Hematoma in a Patient With Severe Thrombocytopenia due to Aplastic Anemia: A Case Report.

Clinical case reports·2026

Same journal

Appendix Mucinous Neoplasm.

Clinical case reports·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 10, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Published on: April 1, 2019

Bilateral Persistent Pupillary Membrane.

Hassan Asadigandomani¹, Mohammad Soleimani^1,2

¹Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences Tehran Iran.

Clinical Case Reports

|November 24, 2025

Summary

This summary is machine-generated.

Persistent pupillary membranes were observed in a 31-year-old man during a routine eye exam. These bilateral, asymptomatic membranes did not cause vision impairment due to a spared central pupillary zone.

Keywords:

amblyopia iris persistent pupillary membrane visual axis

More Related Videos

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Related Experiment Videos

Last Updated: Jan 10, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Published on: April 1, 2019

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Area of Science:

Ophthalmology
Anatomy
Congenital Eye Anomalies

Background:

Persistent pupillary membranes (PPM) are congenital remnants of the fetal pupillary membrane.
PPMs are typically asymptomatic and resolve spontaneously during development.
Persistence of PPMs can occasionally lead to visual disturbances.

Purpose of the Study:

To report a case of bilateral asymptomatic persistent pupillary membranes.
To highlight the anatomical characteristics of PPM that prevent vision impairment.

Main Methods:

Case presentation of a 31-year-old male patient.
Routine ophthalmic examination including visual acuity assessment and slit-lamp biomicroscopy.

Main Results:

Bilateral, asymptomatic persistent pupillary membranes were identified.
A central 1.5 mm pupillary zone remained unaffected by the membranes.
No visual impairment was reported by the patient.

Conclusions:

Persistent pupillary membranes can be asymptomatic and without visual consequence.
The size and location of the unaffected pupillary zone are critical factors in maintaining visual function.
Routine eye exams are important for detecting congenital anomalies like PPM.