Bacterial agent, antibiotic resistance profile and predictors of urinary tract infection among pregnant women attending antenatal care in Ethiopia
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View abstract on PubMed
Summary
This summary is machine-generated.Urinary tract infections (UTIs) in pregnant women in Ethiopia show high rates of antibiotic resistance, particularly to ampicillin. Early diagnosis and understanding resistance patterns are crucial for effective treatment.
Area Of Science
- Medical Microbiology
- Infectious Diseases
- Public Health
Background
- Urinary tract infections (UTIs) are a significant global health concern, affecting both community and hospital settings.
- Pregnant women are particularly vulnerable to UTIs, which can lead to serious complications.
- Understanding the local epidemiology of UTIs is vital for effective management.
Purpose Of The Study
- To determine the prevalence of UTIs among pregnant women in East Wallaga, Ethiopia.
- To identify the common bacterial pathogens causing UTIs in this population.
- To assess the antibiotic susceptibility patterns and risk factors associated with UTIs.
Main Methods
- An institutional-based cross-sectional study was conducted.
- Bacterial isolates were identified using the Kirby-Bauer disk diffusion technique for antibiotic sensitivity testing.
- Statistical significance was determined using a 95% confidence interval and a P-value < 0.05.
Main Results
- The prevalence of UTIs was 14.9%, with 44 out of 296 pregnant women affected.
- Gram-negative bacteria constituted 61.4% of isolates, with Escherichia coli being the most common (40%).
- High resistance rates were observed: 87% to ampicillin and 77.3% exhibited multidrug resistance. History of catheterization and prior UTI were significant risk factors.
Conclusions
- The study reveals alarming levels of antibiotic resistance among UTI-causing bacteria in pregnant women in Ethiopia.
- Early and routine diagnosis of UTIs, along with knowledge of drug-susceptibility patterns, is critical.
- This highlights the need for updated treatment guidelines and antibiotic stewardship programs.
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