Serum LDL level as an indirect marker of erectile dysfunction in male CAD patients

Erectile dysfunction (ED) is a prevalent condition among male patients with coronary artery disease (CAD), often reflecting underlying vascular problems. Recent studies suggest that serum low-density lipoprotein (LDL) levels, a key factor in atherosclerosis, might serve as an indirect marker of ED in this population.

The aim of our study is to analyse correlation between serum LDL level and severity of erectile dysfunction. To assess the prevalence of erectile dysfunction in male CAD patients. To evaluate other potential risk factors contributing to erectile dysfunction in male CAD patients.

From September 2022 to August 2023, 240 CAD patients were analysed for organic ED with the help of IIEF-5 score, and their lipid profile (Cholesterol, Triglyceride, HDL, LDL) were compared.

Mean age in the study group is 47.61± 7.82 years. The overall prevalence of ED among MALE CAD patients was found out to be 73%, with Mean IIEF-5 score of 16.9 with SD 4.89. LDL cholesterol level had a positive correlation with Severity of ED (p value 4.88×10-16, r=-0.7052, r2=0.49). Mean LDL 95.83mg/dl with a standard deviation of 31.37. Serum cholesterol level had a positive correlation with Severity of ED (p value= 2.84×10-9). Mean Cholesterol level is 165.5mg/dl with a SD of 38.66.

Treatment for hyperlipidaemia plays a crucial role in preventing ED, as evidenced by the impact of total cholesterol and LDL in particular on men's erectile function. This highlights the need for a comprehensive approach to managing ED patients.