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Ocular biometric parameter characteristics and influence on refractive power in Chinese children
Chao-Ying Ye1,2,3, Yu-Jia Liu1,2,3, Wen-Qian Xing1,2,3
1Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
Insights
In children aged 3-12, older age correlates with longer axial length (AL) and thinner lenses (LT), with lens thickness significantly impacting refractive power more in younger children. Axial length and anterior chamber depth also increase with age.
Area of Science:
- Ophthalmology
- Pediatric Optometry
- Refractive Error Research
Background:
- Understanding ocular parameter changes is crucial for monitoring refractive status in children.
- Age-related variations in axial length, lens thickness, and anterior chamber depth influence refractive development.
Purpose of the Study:
- To analyze ocular parameters and refractive status in children aged 3-12 years.
- To investigate age-related differences in ocular parameters within specific refractive error groups.
- To determine the impact of age on refractive progression.
Main Methods:
- Collected demographic data, cycloplegic refraction, and ocular parameters from 1504 children's right eyes.
- Analyzed changes in ocular parameters across different age groups.
- Employed multiple linear regression to assess the relationship between age, ocular parameters, and refractive power.
Main Results:
- Lens thickness (LT) decreased with age, while axial length (AL) and anterior chamber depth (ACD) increased.
- Age was associated with AL and LT in high hyperopia; AL, LT, and corneal astigmatism in low myopia.
- Lens thickness showed the highest regression coefficient (β=0.41) for refractive power, with a greater effect in younger children.
Conclusions:
- In children with similar refractive status, increasing age is linked to longer AL and thinner LT.
- Lens thickness is the ocular parameter most significantly influenced by age.
- The lens plays a more substantial role in refractive power for younger children compared to older ones.
Aim:
To analyze ocular parameters and refractive status in children aged 3-12y and to explore differences in these parameters across age groups with identical refractive status for studying refractive progression.
Methods:
Demographic characteristics, cycloplegic refraction data, and ocular parameters of the participants were collected. Changes in ocular parameters were described according to different age groups. After adjusting for refractive factors, the relationship between age and ocular parameters was explored. Standard regression coefficients (β) obtained from multiple linear regressions were used to compare the magnitude of the effect of age on the parameters and ocular components on refractive power.
Results:
Data were collected from the right eyes of 1504 participants. Lens thickness (LT) decreased with age, whereas the axial length (AL) and anterior chamber depth (ACD) increased. In the high-hyperopia group, changes in age were only associated with AL and LT. In the low-myopia group, the increase in age was also associated with corneal astigmatism. In the overall model, the β value for LT was the highest at 0.41, whereas β for ACD and AL was significant in all groups except for the high-hyperopia group. The β value of the LT on refractive power in children was slightly greater in the low age group than in the high age group.
Conclusion:
Among children with the same refractive status, the older the age, the longer the axis length and the thinner the lens. The lens affected refractive power in children in the younger age group more than in the older age group. The ocular parameter most affected by age was LT.
