Related Experiment Video
Updated: Jan 10, 2026
Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
Patient centered comparative evaluation of injectable platelet concentrate with or without micro-needling in the
Anisha Singh1, Chetan Chandra1, Vivek Kumar Bains1
1Department of Periodontology, Saraswati Dental College & Hospital, Lucknow, India.
Aim:
To evaluate the clinical and patient-centered outcomes of Injectable Platelet Concentrate (IPC) and Microneedling (MN) in augmenting thin gingival phenotype (GP).
Materials And Methods:
The present study was a patient-centered, split-mouth, randomized clinical trial involving 26 participants with thin GP who were randomly treated with IPC + MN (Group 1) and IPC-MN (Group 2). Clinician oriented parameters such as Gingival Thickness (GT), Keratinized Tissue Width (KTW) and Probe Visibility (PV) in addition to Patient Reported Outcomes (PROMs) in form of Translucent Tissue Visibility Score (TTVS) for appearance of underlying hard tissue through thin gingiva were measured at baseline, 1 month, 2 months and 3 months. Overall Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD), Gingival Bleeding Index (GBI), Specific PI (S-PI), Specific GI (S-GI), and Specific-GBI (S-GBI) were also assessed for additional information.
Results:
The study demonstrated a significant increase in GT for both treatment groups, with Group 1 (IPC + MN) showing greater augmentation compared to Group 2 (IPC-MN) (p < 0.005). Analysis of PROMs revealed that TTVS significantly decreased, with Group 1 (IPC + MN) showing a complete reduction in translucency at 3 months (0 %) compared to 38.5 % in Group 2 (IPC-MN) (p < 0.005). Overall, PI and GI increased slightly over time, but no significant differences were observed between the groups. S-GBI improved with increasing GT, indicating better tissue stability.
Conclusion:
The combination of IPC and MN significantly enhances GT and reduces gingival translucency, making it a promising approach for managing thin gingival phenotypes. However, the associated decrease in brushing comfort highlights the need for patient-specific considerations when selecting treatment modalities. Future studies should explore long-term outcomes and patient adaptation to increased gingival thickness.
