Related Experiment Video
Updated: Jan 10, 2026

03:47
Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
Published on: September 27, 2024
1.4K
Early Experience With Ultherapy Prime in Asia Pacific: A Pilot Case Series
Joyce Lim1, Tuck Wah Siew2, Yanni Xu3
1From the Joyce Lim Skin and Laser Clinic, Singapore, Singapore.
Plastic and Reconstructive Surgery. Global Open
|November 24, 2025
Summary
Ultherapy Prime effectively improved jawline and neck skin laxity in Asian patients. This microfocused ultrasound treatment was well-tolerated and showed significant aesthetic improvements across diverse demographics.
Area of Science:
- Aesthetics
- Dermatology
- Medical Devices
Background:
- Microfocused ultrasound with real-time visualization is a proven noninvasive skin lifting treatment.
- Ultherapy Prime is an advanced version with enhanced imaging and processing for tissue remodeling.
- Limited data exists on Ultherapy Prime's efficacy in Asian populations.
Purpose of the Study:
- To evaluate the effectiveness and safety of Ultherapy Prime for skin lifting and laxity in Asian patients.
- To assess Ultherapy Prime's impact on jawline and neck sagging.
- To document patient and physician-reported outcomes.
Main Methods:
- Thirty Asian participants with mild-to-severe sagging were treated with Ultherapy Prime.
- A dual-depth treatment protocol using 650+ lines of microfocused ultrasound was applied.
- Outcomes measured included Merz Aesthetics Scale (MAS) scores, Global Aesthetic Improvement Scale (GAIS), and pain scores.
Main Results:
- Most participants showed MAS improvement in neck and jawline by day 90.
- 100% of patients and physicians reported aesthetic improvement (ranging from improved to very much improved) via GAIS.
- The treatment was well-tolerated, with a mean pain score of 4.50.
Conclusions:
- A single Ultherapy Prime treatment effectively improves jawline and neck skin laxity in Asian patients.
- The treatment demonstrates good tolerability across various demographic groups.
- Ultherapy Prime offers a safe and effective option for noninvasive skin tightening in Asians.

