Inflammatory Bowel Disease in Jordanian Children: A Tertiary Center Experience
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View abstract on PubMed
Summary
This summary is machine-generated.Pediatric inflammatory bowel disease (IBD) in Jordan shows Crohn's disease is more common than ulcerative colitis. Limited biologic access necessitates improved therapies and a national IBD registry for better pediatric IBD care.
Area Of Science
- Pediatric Gastroenterology
- Inflammatory Bowel Disease Research
- Clinical Epidemiology
Background
- Pediatric inflammatory bowel disease (IBD) presents unique challenges in diagnosis and management.
- Understanding regional variations in IBD is crucial for global health insights.
- Jordanian pediatric IBD data is limited, necessitating local research.
Purpose Of The Study
- To delineate the clinical characteristics, subtypes, laboratory findings, and outcomes of pediatric IBD in Jordan.
- To compare Jordanian pediatric IBD trends with global and regional data.
- To identify specific needs and challenges in managing pediatric IBD in the region.
Main Methods
- Retrospective review of medical records for pediatric IBD patients (age < 18) at Jordan University Hospital (2015-2022).
- Diagnosis confirmation using the revised Porto criteria.
- Analysis of patient demographics, clinical presentation, disease behavior, laboratory markers, and treatment modalities.
Main Results
- 31 pediatric IBD patients (61.3% male) diagnosed at a mean age of 8.7 years.
- Crohn's disease (51.6%) predominated over ulcerative colitis (29.0%); 38.7% had very early onset IBD (VEO-IBD).
- Common symptoms included diarrhea and abdominal pain; anemia was prevalent (58.1%), with elevated CRP/ESR in over 60%.
Conclusions
- Pediatric Crohn's disease is more prevalent than ulcerative colitis in this Jordanian cohort.
- Limited access to biologic therapies and frequent treatment escalations were observed.
- There is a critical need for enhanced therapeutic strategies and the establishment of a national IBD registry.
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