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Using Over-the-Counter Retail Medication Sales to Detect and Track Influenza-Like Illnesses Including Novel Diseases.
Medrxiv : the Preprint Server for Health Sciences
|November 24, 2025
Summary
Monitoring sales of over-the-counter (OTC) health products offers a novel approach to detect disease outbreaks early. This method can identify unusual health activity and provide timely public health insights.
Area of Science:
- Public Health Surveillance
- Epidemiology
- Data Science in Health
Background:
- Traditional disease surveillance relies on delayed clinical data.
- Early detection of emerging outbreaks is crucial for public health.
- National Retail Data Monitor (NRDM) tracks over-the-counter (OTC) product sales.
Purpose of the Study:
- To evaluate NRDM data for public health surveillance.
- To develop a probabilistic model for estimating influenza-like illness (ILI) activity.
- To assess OTC sales as an early warning system for known and novel diseases.
Main Methods:
- Utilized NRDM data from Allegheny County, PA (2016-2021).
- Developed a probabilistic model using an expectation-maximization (EM) algorithm.
- Estimated daily ILI activity based on OTC purchasing patterns.
Main Results:
- The model estimated ILI counts correlated moderately with emergency department data (r = 0.66).
- Model performance can indicate unusual disease outbreaks.
- Changes in consumer purchasing behavior signal health trends.
Conclusions:
- OTC product sales surveillance is a viable tool for public health.
- This method provides early insights into potential outbreaks.
- It can detect both known and novel disease emergence.
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