Epidemiological and Clinical Changes in RSV-Associated Pneumonia in Children in Mexico Before and During the COVID 19 Pandemic
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View abstract on PubMed
Summary
This summary is machine-generated.Respiratory syncytial virus (RSV) infections in children shifted towards summer and autumn, with increased incidence and older affected children during the COVID-19 pandemic. This highlights changes in RSV epidemiology and seasonality.
Area Of Science
- Pediatric infectious diseases
- Epidemiology
- Virology
Background
- Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children.
- Public health measures during the COVID-19 pandemic temporarily reduced RSV transmission.
- An atypical resurgence of RSV was observed in mid-2021.
Purpose Of The Study
- To compare clinical and epidemiological features of RSV infections in Mexican children before and during the COVID-19 pandemic.
- To analyze changes in RSV seasonality, incidence, and affected demographics.
- To identify risk factors for severe RSV-related pneumonia.
Main Methods
- Comparative ambispective longitudinal epidemiological study with two cohorts (2010-2013 and 2021-2023).
- Inclusion of children under five years diagnosed with RSV-related pneumonia.
- Statistical analyses including t-tests, chi-square, and logistic regression; incidence density calculation.
Main Results
- Mean age of affected children increased from 10 to 15 months.
- RSV activity started earlier (summer months) with higher incidence post-2020.
- RSV type B became more prevalent (58.5% vs. 3.8%), and co-infections increased (60% vs. 39%).
Conclusions
- RSV seasonality has shifted towards summer and autumn.
- Increased incidence and infections in older children were observed during the pandemic period.
- Ongoing surveillance is crucial to understand evolving RSV patterns amidst complex public health scenarios.
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