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Universal Decentralized Cord Blood TSH Screening Should Be Offered as Routine Delivery Care in Limited-Resource
Nitash Zwaveling-Soonawala1,2, Anju Virmani3,4, Aman B Pulungan5
1Department of Pediatric Endocrinology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.
International Journal of Neonatal Screening
|November 24, 2025
Summary
Newborn screening for congenital hypothyroidism is crucial but underutilized globally. A universal, decentralized cord blood TSH screening offers a feasible solution for limited-resource settings, improving early diagnosis and preventing intellectual disability.
Area of Science:
- Neonatal screening
- Endocrinology
- Public health
Background:
- Congenital hypothyroidism (CH) screening prevents intellectual disability, yet global coverage remains low (29.6%).
- Limited screening in Africa and Asia, regions with high birth rates, exacerbates the problem.
- Current newborn screening (NBS) methods are complex and costly, hindering implementation in resource-limited settings.

