Related Experiment Video
Updated: Jan 10, 2026

05:28
Enucleation of the Prostate for the Treatment of Benign Prostatic Hyperplasia Using a 980 nm Diode Laser
Published on: May 5, 2020
2.6K
Effects on Ejaculation Preservation Using Low-Energy Pulsed Thulium:YAG Laser Anatomical Enucleation in High-Volume
Alessandro Giacobbe1, Fabrizio Mele1, Maurizio Barale1
1Department of Urology, Mauriziano Hospital, Turin, Italy.
Journal of Endourology
|November 24, 2025
Summary
A new laser prostate surgery technique effectively treats benign prostatic hyperplasia (BPH) while preserving antegrade ejaculation. This pulsed thulium:YAG laser method shows promise for improving urinary flow and sexual function in BPH patients.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Laser Technology
Background:
- Benign prostatic hyperplasia (BPH) significantly impacts lower urinary tract symptoms and quality of life.
- Traditional BPH treatments can compromise ejaculatory function.
- There is a need for effective BPH treatments that preserve sexual health.
Purpose of the Study:
- To evaluate the efficacy of a pulsed thulium:YAG laser anatomical enucleation technique for high-volume BPH.
- To assess the technique's impact on preserving antegrade ejaculation.
- To determine the procedure's effectiveness in relieving prostatic obstruction.
Main Methods:
- Prospective study of 50 high-volume BPH patients.
- Utilized a pulsed thulium:YAG laser for anatomical enucleation, sparing key structures.
- Assessed outcomes using IPSS, QoL, and MSHQ-EjD SF preoperatively and at 6 months postoperation.
Main Results:
- Significant improvements in International Prostate Symptom Index (IPSS) and Quality of Life (QoL) scores.
- Mean maximum flow rate (Qmax) significantly increased, with reduced postvoid residual (PVR) volume.
- Antegrade ejaculation was preserved in 70% of patients, with no significant negative impact on other ejaculatory parameters.
Conclusions:
- The pulsed thulium:YAG laser anatomical enucleation technique is a promising option for BPH treatment.
- This method effectively relieves obstruction while preserving antegrade ejaculatory function.
- Larger randomized controlled studies are needed to validate these findings for broader clinical adoption.

