Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Incomplete Dominance01:43

Incomplete Dominance

29.6K
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
29.6K
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

978
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
978
Human Genetics01:28

Human Genetics

1.4K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.4K
Epistasis Analysis01:09

Epistasis Analysis

5.6K
Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
5.6K
Pedigree Analysis01:35

Pedigree Analysis

88.7K
Overview
88.7K
Genetic Lingo01:11

Genetic Lingo

113.6K
Overview
113.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An interpretable machine learning framework for dog breed inference and ancestry decomposition.

bioRxiv : the preprint server for biology·2026
Same author

Impact of preanalytical factors on liquid biopsy in the canine cancer model.

Communications medicine·2026
Same author

Critical Questions in Genomic Diagnostics for Veterinary Oncology: What We Need to Know.

Veterinary and comparative oncology·2026
Same author

Blood biomarkers and breed genetics of aging in pet dogs.

bioRxiv : the preprint server for biology·2026
Same author

Genomic information increases prediction accuracy of behavior traits of Labrador Retrievers used as guide dogs.

Genetics, selection, evolution : GSE·2026
Same author

Multi-omic Longitudinal Analysis of Canine Osteosarcoma Identifies Inter-Patient Heterogeneity and Immune Enrichment in Metastatic Lesions.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Jan 10, 2026

The Other End of the Leash: An Experimental Test to Analyze How Owners Interact with Their Pet Dogs
08:59

The Other End of the Leash: An Experimental Test to Analyze How Owners Interact with Their Pet Dogs

Published on: October 13, 2017

18.2K

Genetic testing predicts appearance but not behavior in dogs.

Kathryn A Lord1,2, Vista Sohrab1,2,3, Kasia Bryc2,4

  • 1Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA 01655.

Proceedings of the National Academy of Sciences of the United States of America
|November 24, 2025
PubMed
Summary

Genetic tests for dog behavior lack predictive accuracy. Current genetic tests for dog personality traits are unreliable, as behavior is complex and influenced by environment, not just a few genes.

Keywords:
artificial selectionbehaviordoggenetic testinggenomic prediction

More Related Videos

In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

21.2K
Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy
10:30

Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy

Published on: May 24, 2016

19.2K

Related Experiment Videos

Last Updated: Jan 10, 2026

The Other End of the Leash: An Experimental Test to Analyze How Owners Interact with Their Pet Dogs
08:59

The Other End of the Leash: An Experimental Test to Analyze How Owners Interact with Their Pet Dogs

Published on: October 13, 2017

18.2K
In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

21.2K
Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy
10:30

Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy

Published on: May 24, 2016

19.2K

Area of Science:

  • Canine genetics
  • Animal behavior
  • Genomic prediction

Background:

  • Genetic testing for dog behavioral and personality traits is commercially available.
  • The predictive accuracy of these tests has not been rigorously validated.
  • Community science initiatives offer large datasets for such evaluations.

Purpose of the Study:

  • To evaluate the reliability and predictive accuracy of genetic tests for canine behavioral traits.
  • To investigate the association between genetic variants and individual-level behavioral phenotypes in dogs.
  • To identify potential confounders in previous genetic studies of dog behavior.

Main Methods:

  • Analysis of genetic data and individual-level behavioral phenotypes from over 3,000 dogs in the Darwin's Ark community science initiative.
  • Testing associations between candidate genetic variants and behavioral traits.
  • Comparing results with previous studies that used breed-average phenotypes.

Main Results:

  • No significant associations or predictive power were found for candidate variants related to behavioral traits.
  • Strong associations were identified between genetic variants and aesthetic traits (e.g., height, leg length, ear shape).
  • Previous studies using breed-average phenotypes may have been confounded by population structure.

Conclusions:

  • Current genetic tests for dog behavior are unreliable due to the polygenic and complex nature of behavior.
  • Environmental influences and moderate heritability limit the accuracy of genomic predictions for dog behavior.
  • Developing accurate genetic predictions for complex canine traits requires large cohorts with individually measured phenotypes to improve dog health and welfare.