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Updated: Jan 10, 2026

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Parents' perception and knowledge regarding blood transfusion in a tertiary care paediatric centre in India
Jay Bisht1, Kriti Batni1, Satyam Arora1
1Department of Transfusion Medicine, Post Graduate Institute of Child Health (PGICH), Noida, Uttar Pradesh, India.
Insights
Parental knowledge of pediatric blood transfusion risks, including transfusion-transmitted infections (TTIs), is limited. Higher education and regular transfusions improve awareness, highlighting the need for targeted patient education to enhance transfusion safety.
Area of Science:
- Hematology
- Pediatric Medicine
- Public Health
Background:
- Paediatric transfusion therapy is vital for managing various childhood disorders.
- Parental understanding of transfusion risks, such as transfusion-transmitted infections (TTIs) and adverse reactions, is not well-documented.
Purpose of the Study:
- To assess parental knowledge, attitudes, and practices (KAP) concerning paediatric blood transfusions.
- To identify factors influencing parental awareness of transfusion risks.
Main Methods:
- A prospective, cross-sectional study was conducted over six months at a tertiary care children's hospital in India.
- A structured questionnaire was used to evaluate parental knowledge regarding blood transfusions.
Main Results:
- Only 51.3% of parents knew their child's blood group, and 76.1% identified the correct blood component.
- Awareness of transfusion-transmitted infections (TTIs) screened in donated blood (25.9%) and leukoreduction (2%) was notably low.
- Higher parental education and children on chronic transfusion therapy were associated with significantly better knowledge (p < 0.001).
Conclusions:
- Significant gaps in parental knowledge regarding TTIs and leukoreduction were identified.
- Parental education level and exposure to chronic transfusion therapy are key factors influencing awareness.
- Targeted educational interventions are recommended to improve informed consent and transfusion safety.
Background And Objectives:
Paediatric transfusion therapy is critical for managing haematological and genetic disorders. However, parental knowledge about transfusion risks, including transfusion-transmitted infections (TTIs) and adverse reactions, remains largely unexplored. This study assessed parental knowledge, attitudes and practices (KAP) regarding paediatric blood transfusions.
Materials And Methods:
A prospective cross-sectional study was conducted at a tertiary care children's hospital in India over 6 months. A structured questionnaire evaluated parental knowledge.
Results:
Among 230 parents (51.7% mothers), 51.3% knew their child's ABO blood group and 76.1% correctly identified the required blood component. Awareness of TTIs screened in donated blood (25.9%) and leukoreduction (2%) was low. Parents of children on chronic transfusion therapy demonstrated significantly better knowledge (p = 0.001 for blood group, p < 0.001 for blood component). Education level strongly predicted transfusion-related knowledge: parents with high school education were 16.8 times more likely to know the blood group (odds ratio [OR] = 16.84, p < 0.001) and 10.4 times more likely to identify the correct blood component (OR = 10.44, p = 0.026).
Conclusion:
Significant gaps exist in parental knowledge, particularly regarding TTIs and leukoreduction. Higher education and chronic transfusion exposure improve awareness. Graduate education was linked to a better understanding of TTIs (OR = 2.95, p = 0.038). Targeted education can enhance transfusion safety and the consent process.
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