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Cohort Profile: Shanghai University of Sport (SUS) Longitudinal Cohort Study of Alumni Health Tracking
Huanyu Wang1, Ruwen Wang1, Qin Sun1
1School of Exercise and Health, Shanghai University of Sport.
Background:
The Shanghai University of Sport (SUS) Longitudinal Cohort Study (SUS Cohort) was established to investigate the influence of lifestyle and modifiable behavioral factors in early adulthood on the development of non-communicable diseases (NCDs) later in life. The cohort aims to identify novel biomarkers and explore mechanisms underlying chronic diseases using a multi-omics approach.
Methods:
The SUS Cohort study is a prospective cohort study of undergraduate students between 2018 and 2019, with follow-ups conducted every 2 years during early adulthood and every 10 years thereafter. Comprehensive data collection includes body composition measurements, lifestyle surveys, physical fitness tests, and clinical laboratory tests. Multi-omics analysis, including genome-wide genotyping, gut microbiome, and serum metabolome, is integrated to provide insights into disease pathophysiology.
Results:
A total of 1,758 participants aged 18 to 22 (mean age 18.64; standard deviation, 3.15) years were conducted from baseline surveys, with a follow-up period between September 2021 and September 2022. The median age at baseline was 18 years, and female participants accounted for 49.5% of the cohort (n = 870). Of the initial participants, 1,055 individuals (60%) completed the follow-up.
Conclusion:
The SUS Cohort provides multidimensional data to study how early-life factors influence long-term health outcomes.
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