Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

$X-ray Diffraction of Biological Samples$ 01:10

X-ray Diffraction of Biological Samples

X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are scattered by the electron clouds around the sample atoms. The X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Low-temperature liquid-assisted vibrational stress-relief strategy enables stable and efficient perovskite solar cells.

Nature communications·2026

Same author

Structural Engineering of Rare-Earth Nanomaterials.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Long-distance lanthanide migration regulated by interfacial lattice strain in nanostructures.

Nature communications·2026

Same author

Dual-substrate-based full-color fluorescent probe TPE-4PA@Tb/Eu-GMP-acac ICPs for alkaline phosphatase detection and its on-site application for algal bloom alert.

Talanta·2026

Same author

Inverted perovskite solar cells: from fundamentals to scalable commercialization.

Chemical Society reviews·2026

Same author

Hybrid Seeding-Template Modulation of Sn-Pb Perovskite Crystallization for High-Efficiency All-Perovskite Tandem Solar Cells.

Angewandte Chemie (International ed. in English)·2026

Search research articles

Related Experiment Video

Updated: Jan 10, 2026

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

Published on: September 30, 2022

Scattering-free lanthanide-ionic liquid scintillators for high-resolution and adaptive X-ray imaging.

Jian Qiu^1,2, Chang Gu^1,2, Mingtai Chen^1,2

¹Department of Chemistry, National University of Singapore, Singapore, Singapore.

Nature Communications

|November 25, 2025

Summary

This study introduces a novel liquid scintillator for X-ray imaging, overcoming light scattering issues. The new material achieves high light transmittance and enhanced imaging resolution, offering a stable and biocompatible solution.

More Related Videos

Hyperspectral Imaging as a Tool to Study Optical Anisotropy in Lanthanide-Based Molecular Single Crystals

Hyperspectral Imaging as a Tool to Study Optical Anisotropy in Lanthanide-Based Molecular Single Crystals

Published on: April 14, 2020

Fabrication Procedures and Birefringence Measurements for Designing Magnetically Responsive Lanthanide Ion Chelating Phospholipid Assemblies

Fabrication Procedures and Birefringence Measurements for Designing Magnetically Responsive Lanthanide Ion Chelating Phospholipid Assemblies

Published on: January 3, 2018

Related Experiment Videos

Last Updated: Jan 10, 2026

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

Published on: September 30, 2022

Hyperspectral Imaging as a Tool to Study Optical Anisotropy in Lanthanide-Based Molecular Single Crystals

Hyperspectral Imaging as a Tool to Study Optical Anisotropy in Lanthanide-Based Molecular Single Crystals

Published on: April 14, 2020

Fabrication Procedures and Birefringence Measurements for Designing Magnetically Responsive Lanthanide Ion Chelating Phospholipid Assemblies

Fabrication Procedures and Birefringence Measurements for Designing Magnetically Responsive Lanthanide Ion Chelating Phospholipid Assemblies

Published on: January 3, 2018

Area of Science:

Materials Science
Medical Imaging
Optics

Background:

X-ray imaging relies on efficient light transmission through scintillation screens.
Solid and solution-based scintillators face challenges with photon scattering and attenuation.
Existing methods for improving light extraction in solid-state scintillators have limitations in reducing internal scattering.

Purpose of the Study:

To develop a liquid scintillator strategy that eliminates light scattering for improved X-ray imaging.
To leverage coordination chemistry between lanthanide ions and ionic liquid ligands for enhanced optical properties.
To achieve high scintillation light transmittance and superior spatial resolution in X-ray detectors.

Main Methods:

Utilized in-situ coordination chemistry between lanthanide ions and ionic liquid ligands.
Developed a liquid scintillator with high structural homogeneity and optical transparency.
Employed self-absorption-free lanthanides to minimize signal loss.

Main Results:

Achieved over 93% scintillation light transmittance, eliminating light scattering.
Boosted X-ray imaging spatial resolution to 26 lp mm⁻¹ with a 1 mm scintillation screen.
Demonstrated long-term stability and environmental compatibility of the ionic liquid-based scintillators.

Conclusions:

The liquid scintillator strategy effectively overcomes light scattering limitations in X-ray imaging.
The developed scintillators offer high performance, stability, and biocompatibility.
The fluidic and shape-adaptive nature enables novel applications like zoom scintillation lenses for advanced X-ray detection.