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Digital Versus In-Person Physical Therapy in Adults With Musculoskeletal Conditions: Retrospective Matched-Cohort
Beatriz Domingues1, Ana P Pereira1, Akshat Pradhan1
1Clinical Research & Dev, Sword Health, New York, NY, United States.
Background:
Musculoskeletal (MSK) disorders are leading causes of disability worldwide, with clinical guidelines recommending physical therapy-based interventions. Digital MSK programs offer an alternative to address logistical and socioeconomic barriers to regular in-person care. However, evidence comparing surgical use between digital and in-person physical therapy remains limited, particularly for low-value procedures.
Objective:
This study aimed to evaluate the 12-month incidence of MSK surgery and low-value surgical procedures among participants initiating a multimodal Digital Care Program (DCP) versus a matched-cohort initiating in-person physical therapy.
Methods:
Retrospective, matched-cohort study, using exact and propensity matching, with a Health Insurance Portability and Accountability Act (HIPAA)-deidentified US nationwide merged claims dataset (July 2022-February 2025). Eligible adults had spine, knee, hip, or shoulder conditions, ≥24 months uninterrupted health insurance coverage to an employer-sponsored DCP, and no MSK surgery in the prior year. The intervention group (IG) participated in a DCP combining exercise, education, and cognitive behavioral therapy, with real-time biofeedback and remote physical therapist oversight. The comparator group (CG) initiated in-person physical therapy, identified from a third-party claims database, using relevant MSK ICD-10 (International Statistical Classification of Diseases, Tenth Revision) codes as primary diagnosis. The primary outcome was the incidence of any MSK surgery within 12 months; the secondary outcome was the incidence of low-value surgery based on Choosing Wisely-aligned definitions. Cohort characteristics were compared using t test and chi-square test. Risk ratios (RRs) were calculated overall and by pain site, age group, and Social Deprivation Index.
Results:
In a matched cohort of 4190 individuals, predominantly middle-aged (~52 years old) women (1335/2095, 63.7%) with spinal pain (1123/2095, 53.6%), participation in the digital program was linked to a 58% (95% CI 49-66) lower relative risk of surgery at 12 months compared to those initiating in-person physical therapy (RR 0.42, 95% CI 0.34-0.52; E-value=4.19 [lower CI 3.29]). For surgeries categorized as low-value, IG was associated with 82% (95% CI 68-90) lower relative risk (RR 0.17, 95% CI 0.09-0.31; E-value=11.24 [lower CI 5.91]). Overall MSK surgical trends were consistent across pain sites, with greatest relative differences for knee (IG: 40/414 9.7% vs CG: 122/414, 29.5%; RR 0.26; 95% CI 0.17-0.38) followed by hip (19/203, 9.4% vs 42/203, 20.7%; RR 0.40; 95% CI 0.22-0.71). Lower surgery incidences in the IG (overall and low-value) were found across all socioeconomic and age strata.
Conclusions:
This real-world study demonstrated, for the first time, that participation in a digital MSK program was associated with substantially lower incidences of both overall and low-value surgeries compared to those who opted for in-person physical therapy among commercially-insured adults. These findings suggest that digital MSK programs can mitigate access barriers, promote adherence to guideline-concordant care, and reduce unnecessary procedures, including among underserved populations.

