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Related Concept Videos

Endocrine Signaling01:45

Endocrine Signaling

67.7K
Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
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What is the Endocrine System?00:46

What is the Endocrine System?

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The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
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The Endocrine System01:29

The Endocrine System

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The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
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An Overview of the Endocrine System01:10

An Overview of the Endocrine System

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The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
13.0K
Structures of the Endocrine System00:59

Structures of the Endocrine System

11.4K
The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
11.4K
Intracellular Hormone Receptors01:08

Intracellular Hormone Receptors

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Lipid-soluble hormones diffuse across the plasma and nuclear membrane of target cells to bind to their specific intracellular receptors. These receptors act as transcription factors that regulate gene expression and protein synthesis in the target cell
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Related Experiment Video

Updated: Jan 10, 2026

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
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EndoCompass Project: Endocrine Laboratory Medicine.

Annemieke C Heijboer1,2, Jacquelien J Hillebrand3,4, Brian Keevil5

  • 1Endocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC, Location University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands, a.heijboer@amsterdamumc.nl.

Hormone Research in Paediatrics
|November 25, 2025
PubMed
Summary

Strategic research priorities in endocrine science were identified to address hormone health challenges. The EndoCompass project highlights the need for quality assurance and innovative technologies to improve patient care and research reliability.

Keywords:
AnalysisBiomarkerDiversityDynamic testingHormoneImmunoassayLC-MS/MSPre-analysisStandardizationSustainability

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Area of Science:

  • Endocrinology and hormone health research.
  • Laboratory medicine and diagnostic advancements.

Background:

  • Endocrine science is underrepresented in EU research despite its impact on human wellbeing.
  • A gap exists between the societal impact of endocrine disorders and research prioritization.
  • National funding often overlooks endocrinology, necessitating strategic initiatives.

Purpose of the Study:

  • To identify and promote strategic research priorities in endocrine science.
  • To address critical hormone-related health challenges through focused research.
  • To bridge the gap in research prioritization for endocrine disorders.

Main Methods:

  • Analysis of the EU CORDIS database (Horizon 2020 framework).
  • Expert examination of challenges and opportunities in hormone measurements.
  • Focus on analytical quality, method validation, and emerging technologies.

Main Results:

  • Priorities include optimizing pre-analytical processes and standardizing endocrine tests.
  • Development of personalized reference intervals and innovation in biomarker discovery.
  • Emphasis on artificial intelligence, health economics, and sustainable laboratory practices.

Conclusions:

  • An evidence-based roadmap for advancing endocrine laboratory medicine.
  • Supports strategic investment in quality assurance and innovative technologies.
  • Aims to enhance research reliability and improve patient outcomes in endocrine diseases.