Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Challenging the prescientific frameworks of criminal justice: neurobiology and criminolytic interventions in the legalome era.

Frontiers in psychology·2026
Same author

The gut is guilty! Will legalomics transform forensic and legal psychology?

Frontiers in psychology·2026
Same author

Atypical Neonatal Cutaneous Lupus.

Indian journal of pediatrics·2026
Same author

The Metabolic Mind: Revisiting Glucose Metabolism and Justice Involvement in Neurolaw.

NeuroSci·2025
Same author

Reimagining criminal accountability: microbial and omics perspectives in the evolution of legal responsibility.

Journal of law and the biosciences·2025
Same author

Genetic and genomic resources for accelerating marker-assisted ideotype breeding in pigeonpea (Cajanus cajan L. Millsp.).

Journal of experimental botany·2025

Related Experiment Video

Updated: Jan 10, 2026

Label-free Single Molecule Detection Using Microtoroid Optical Resonators
08:53

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Published on: December 29, 2015

9.7K

Fano-engineered high-Q compact nested ring resonator based photonic device for advanced multi-analyte biosensing

Pragya Mishra1, Tushar Gaur2, Talabattula Srinivas3

  • 1Department of Electrical Communication Engineering, Indian Institute of Science, Bangalore, 560012, Karnataka, India. pragyamishra@iisc.ac.in.

Scientific Reports
|November 25, 2025
PubMed
Summary

This study introduces a compact Fano-engineered Nested Ring Resonator (NRR) for enhanced biosensing. The novel NRR design achieves high sensitivity and simultaneous multi-analyte detection, outperforming traditional resonators for lab-on-chip applications.

Keywords:
Fano resonanceMicroring resonatorNested ring resonatorPhotonic biosensors

More Related Videos

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

13.2K
Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

9.7K

Related Experiment Videos

Last Updated: Jan 10, 2026

Label-free Single Molecule Detection Using Microtoroid Optical Resonators
08:53

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Published on: December 29, 2015

9.7K
Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

13.2K
Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

9.7K

Area of Science:

  • Photonics
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Conventional resonators lack sensitivity for advanced biosensing.
  • Existing designs are often complex or large-scale, hindering integration.

Purpose of the Study:

  • To develop a compact, CMOS-compatible Fano-engineered Nested Ring Resonator (NRR) for superior biosensing.
  • To achieve high sensitivity and multi-analyte detection capabilities.

Main Methods:

  • Utilized Fano-engineering principles in a Nested Ring Resonator (NRR) design.
  • Achieved high-contrast, high-Q Fano resonances via minimal structural modification.
  • Analyzed device performance including extinction ratio, spectral contrast, Q-factor, sensitivity, and FOM.

Main Results:

  • The NRR design supports three distinct Fano resonances with sharp spectral asymmetries.
  • Achieved an extinction ratio >50 dB, spectral contrast of 99.95%, Q-factor of 7192.
  • Demonstrated maximum sensitivity of 583.3 nm/RIU and FOM of 1587 RIU⁻¹, outperforming conventional resonators.
  • Enabled simultaneous multi-analyte detection for refractive indices from 1.33-1.50 RIU.

Conclusions:

  • Fano-engineered NRRs offer a practical, scalable, and integrable platform for next-generation photonic biosensing.
  • The device's tunability and high performance pave the way for advanced lab-on-chip systems.
  • Minimal structural modification leads to significant performance enhancement in biosensing devices.