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Fano-engineered high-Q compact nested ring resonator based photonic device for advanced multi-analyte biosensing
Pragya Mishra1, Tushar Gaur2, Talabattula Srinivas3
1Department of Electrical Communication Engineering, Indian Institute of Science, Bangalore, 560012, Karnataka, India. pragyamishra@iisc.ac.in.
Scientific Reports
|November 25, 2025
Summary
This study introduces a compact Fano-engineered Nested Ring Resonator (NRR) for enhanced biosensing. The novel NRR design achieves high sensitivity and simultaneous multi-analyte detection, outperforming traditional resonators for lab-on-chip applications.
Area of Science:
- Photonics
- Nanotechnology
- Biomedical Engineering
Background:
- Conventional resonators lack sensitivity for advanced biosensing.
- Existing designs are often complex or large-scale, hindering integration.
Purpose of the Study:
- To develop a compact, CMOS-compatible Fano-engineered Nested Ring Resonator (NRR) for superior biosensing.
- To achieve high sensitivity and multi-analyte detection capabilities.
Main Methods:
- Utilized Fano-engineering principles in a Nested Ring Resonator (NRR) design.
- Achieved high-contrast, high-Q Fano resonances via minimal structural modification.
- Analyzed device performance including extinction ratio, spectral contrast, Q-factor, sensitivity, and FOM.
Main Results:
- The NRR design supports three distinct Fano resonances with sharp spectral asymmetries.
- Achieved an extinction ratio >50 dB, spectral contrast of 99.95%, Q-factor of 7192.
- Demonstrated maximum sensitivity of 583.3 nm/RIU and FOM of 1587 RIU⁻¹, outperforming conventional resonators.
- Enabled simultaneous multi-analyte detection for refractive indices from 1.33-1.50 RIU.
Conclusions:
- Fano-engineered NRRs offer a practical, scalable, and integrable platform for next-generation photonic biosensing.
- The device's tunability and high performance pave the way for advanced lab-on-chip systems.
- Minimal structural modification leads to significant performance enhancement in biosensing devices.

