Cumulative effect of intrinsic capacity domains on geriatric syndromes and functionality in older inpatients
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View abstract on PubMed
Summary
This summary is machine-generated.Intrinsic capacity (IC) decline is common in older adults and predicts geriatric syndromes like frailty and falls. Assessing IC domains can help identify at-risk individuals for targeted interventions.
Area Of Science
- Gerontology
- Geriatric Medicine
- Public Health
Background
- Intrinsic capacity (IC) is a WHO-defined composite of physical and mental capacities, crucial for assessing functional reserve in older adults.
- IC encompasses five domains: locomotion, vitality, cognition, psychological well-being, and sensory function.
- Understanding the link between IC and geriatric syndromes is vital for effective healthcare strategies.
Purpose Of The Study
- To investigate the associations between intrinsic capacity domains and common geriatric syndromes in hospitalized older adults.
- To identify specific IC domains that predict geriatric syndromes.
- To inform the development of targeted interventions for at-risk older adults.
Main Methods
- A retrospective observational study included 245 hospitalized patients aged 60 years and older.
- Intrinsic capacity was assessed using gait speed, sensory function, cognitive tests (S-MMSE), quality of life (EuroQOL-5D), and nutritional status (Mini Nutritional Assessment).
- Geriatric syndromes including frailty, sarcopenia, falls, incontinence, and functional impairments (ADL/IADL) were evaluated using logistic regression models.
Main Results
- Nearly 60% of participants exhibited moderate to severe IC decline (score ≤ 2).
- Cognitive and vitality impairments were strongly associated with ADL/IADL disability (p < 0.001).
- Locomotor and vitality impairments predicted frailty and sarcopenia (p < 0.01), while cognitive impairment increased fall risk significantly (OR = 5.86).
Conclusions
- Intrinsic capacity impairments, especially in cognition, vitality, and locomotion, are prevalent in hospitalized older adults.
- These IC impairments are significant predictors of major geriatric syndromes.
- Routine IC assessment is recommended to identify individuals at risk and guide personalized interventions.
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