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Published on: November 9, 2016
Cystoscopic injection of botulinum toxin for urgency incontinence
Siv Svennevik Myhr1, Hjalmar A Schiøtz1
1Gynekologisk avdeling, Sykehuset i Vestfold, Tønsberg.
Background:
Urgency incontinence is a common condition that can be difficult to treat. Cystoscopic injection of botulinum toxin into the bladder wall is a treatment option when conservative treatment has failed. The aim of the study was to evaluate the treatment outcomes and clinical benefits of botulinum toxin injection.
Material And Method:
We performed a retrospective record-based study at the Department of Gynaecology, Vestfold Hospital, of women who received intravesical botulinum toxin for urgency incontinence in the period 2014 - 2022 after failing to respond to conservative treatment. The primary endpoint was treatment satisfaction. Secondary endpoints were self-reported continence, repeated injections, treatment interval and complications.
Results:
A total of 167 women received treatment, with 403 injections administered. At the outpatient follow-up six months post-injection, 297/391 (76 %) reported being satisfied with the treatment and 272/384 (71 %) reported having regained continence. One or more complications were recorded in 79 of 395 (20 %) injections: 48 urinary tract infections, 25 cases requiring catheterisation due to impaired bladder emptying, and 6 cases of pain.
Interpretation:
Cystoscopic injection of botulinum toxin may be useful when conservative treatment for urgency incontinence has not led to adequate improvement. However, the method is not without risk of complications.
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