Related Experiment Video
Updated: Jan 10, 2026
An In Vitro Dissolution Determination of Multi-Index Components in Tibetan Medicine Rhodiola Granules
Published on: November 4, 2022
A User-Centric Comprehension Assessment of Prescription Drug Package Inserts in China: A Cross-Sectional Study
Weiwei Zhang1,2, Li Du3, Shu Tan4
1Department of Clinical Pharmacy, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine Tsinghua University Beijing China.
Background:
Drug package inserts (DPIs) are crucial to ensure patients use drugs appropriately. Currently, only standard DPIs are available in China. Users' comprehension of standard DPIs and patient-centered DPIs, and the factors influencing their comprehension, remain poorly understood.
Aim:
Our objective was to evaluate and compare users' comprehension of standard DPIs and patient-centered DPIs. Additionally, we aimed to explore the association between DPI types and users' comprehension and other influencing factors.
Methods:
We selected two standard DPIs and developed two corresponding patient-centered DPIs for examination in 258 participants. Participants were divided into four groups (standard DPI A and B groups, patient DPI A and B groups) and interviewed using a structured questionnaire to test their comprehension of DPIs. We scored the participants' responses and recorded the time taken during the interviews. Regression models were employed to analyze the association between DPI types and comprehension.
Results:
Participants in the patient DPI groups scored significantly higher than those in the standard DPI groups [9.47 (±4.56) versus 6 (±4.02) in the DPI A group; 11.94 (±2.99) versus 9.25 (±2.70) in the DPI B group, p < 0.001]. Participants in the patient DPI groups spent less time during the interviews compared to those in the standard DPI groups (543 [±274.74] s versus 776.11 [±264.03] s in the DPI A group and 457.25 [±213.01] s versus 729.55 [±278.14] s in the DPI B group, p < 0.001). Patient-centered DPIs were positively associated with good comprehension (OR: 80.97; 95% CI: 9.77~670.76; p < 0.001) and negatively associated with time consumption (Coef.: -230.20; 95% CI: -299.13, -161.27; p < 0.001). Education level, age, and income were also identified as potential contributors.
Conclusions:
Comparative analysis showed patient-centered DPI design significantly improves medication comprehension, supporting its use for effective information delivery.
More Related Videos
04:34Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
09:16Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method
Published on: May 12, 2023
Related Concept Videos
01:28Dosage Regimens: Designs and Approaches
01:02Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
01:15Drug Dosage Regimen: Overview
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
01:17Drug Absorption: Overview
When drugs are injected intravenously, they directly enter the systemic circulation. Alternatively, orally administered drugs navigate through the gastrointestinal (GI)...
01:15Drug Dosing: Geriatric Patients
01:16Drug Delivery: Overview
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...