Jove
Visualize
Contact Us

Related Concept Videos

Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Kubler Ross's Stages of Dying01:21

Kubler Ross's Stages of Dying

Elisabeth Kübler-Ross significantly advanced psychology's understanding of the process of dying with her influential book, On Death and Dying (1969). She focused on studying terminally ill individuals and outlined five stages commonly experienced when coping with death: denial, anger, bargaining, depression, and acceptance.
In denial, individuals reject the reality of their condition, often thinking, "This isn't true; I feel fine," as a way to protect themselves from emotional distress. Anger...
Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combining self-regulation and poverty reduction to prevent depression and anxiety among adolescents experiencing multi-dimensional poverty in Colombia, Nepal and South Africa: study protocol of a pilot 4-arm cluster randomised controlled trial.

Pilot and feasibility studies·2026
Same author

Contextually salient barriers and facilitators to implementing community-based mental health interventions delivered by non-specialists in Senegal: A qualitative study.

Global mental health (Cambridge, England)·2026
Same author

Transcultural translation and adaptation of EuroQol's EQ-5D-5L for Nepal: process description and recommendations for an interpretation guide.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026
Same author

Combining neurobiological markers and a sociodemographic risk score to predict adolescent depression - An IDEA RiSCo prospective cohort study.

Molecular psychiatry·2026
Same author

Barriers and facilitators to identifying depression in adolescents: A cross-cultural qualitative study in Brazil, Nepal, and Nigeria.

PLOS mental health·2026
Same author

A guide to selecting psychological interventions that can be delivered by people who are not mental health specialists in low-resource settings.

PLOS global public health·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 25, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

Why can't we talk about suicide?

Brandon A Kohrt1

  • 1Center for Global Mental Health Equity, Department of Psychiatry and Behavioral Health, George Washington University, Washington, DC, USA.

Global Mental Health (Cambridge, England)
|November 26, 2025
PubMed
Summary
This summary is machine-generated.

Rethinking how we discuss suicide is crucial for improving mental health care. An empathy-guided approach can enhance suicide prevention trainings, programs, and data quality, ensuring support for those in distress.

Keywords:
educationethicsliabilitymental healthsuicide

More Related Videos

A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses
06:42

Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses

Published on: September 28, 2018

Related Experiment Videos

Last Updated: May 25, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses
06:42

Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses

Published on: September 28, 2018

Area of Science:

  • Mental Health Research
  • Public Health
  • Suicidology

Background:

  • Mental health improvements lag behind other disease areas.
  • Challenges in primary care detection, service delivery, and data collection persist.
  • The discourse surrounding suicide significantly impacts engagement and program effectiveness.

Purpose of the Study:

  • To examine the impact of communication strategies on mental health care, particularly suicide.
  • To advocate for a shift from medico-legal framing to an empathy-guided approach in suicide discussions.
  • To identify how communication influences training, program adoption, and data quality.

Main Methods:

  • Analysis of communication framing in suicide discussions.
  • Review of medico-legal protocols and their impact on care.
  • Incorporation of lived experience and bereavement perspectives.

Main Results:

  • Protocol-heavy, medico-legal framing detracts from emotional engagement with suicidal individuals.
  • Fear and powerlessness contribute to logistical, legal, and clinical pushback.
  • An empathy-guided approach can foster better engagement and support.

Conclusions:

  • Shifting the discourse on suicide towards empathy is essential for public health.
  • This approach can improve suicide prevention trainings, psychosocial program adoption, and mental health data.
  • Prioritizing emotional processing and collaboration strengthens support systems for individuals experiencing suicidality.