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Updated: Jan 10, 2026

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
Published on: February 16, 2024
Sequential Gastric MALT Lymphoma and Early Signet Ring Cell Adenocarcinoma in a Patient With Chronic Hepatitis B and
Vincent Pinkert1, Arnab Mitra2, Siddharth Javia2
1School of Medicine, Oregon Health & Science University, Portland, OR.
Abstract:
We present the case of a 49-year-old man with cirrhosis secondary to chronic hepatitis B and a history of Helicobacter pylori-positive gastric mucosa-associated lymphoid tissue (MALT) lymphoma, who was later found to have an incidental early-stage signet ring cell adenocarcinoma during surveillance. This case highlights the role of chronic inflammation in gastric carcinogenesis and underscores the importance of long-term endoscopic monitoring and the utility of endoscopic submucosal dissection in appropriately selected patients.
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