Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Deleterious Substances in Aggregate01:25

Deleterious Substances in Aggregate

513
Deleterious substances in aggregates can be detrimental to the quality and durability of concrete. These substances include organic impurities like loam, which interfere with cement hydration and are usually present in the sand. These prevent a good bond between aggregate and cement paste. Organic impurities can be detected using the colorimetric test, where the darkness of a solution after agitation indicates the level of organic content.
Another type of impurity is clay and fine material that...
513
Global Regulatory Systems01:28

Global Regulatory Systems

572
Global regulatory systems in bacteria enable rapid and coordinated responses to environmental changes by integrating sensory inputs with gene expression, ensuring efficient adaptation to fluctuating conditions. Key global regulatory mechanisms include regulons, two-component systems, sigma factors, and secondary messengers.Regulons and Global RegulatorsA regulon is a collection of genes and operons controlled by a common global regulator. These regulators enable bacteria to prioritize resource...
572
Data Reporting and Recording01:24

Data Reporting and Recording

5.3K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.3K
Minerals01:26

Minerals

1.0K
Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
 
Major...
1.0K
Alkali Metals03:06

Alkali Metals

24.1K
Group 1 elements are soft and shiny metallic solids. They are malleable, ductile, and good conductors of heat and electricity. The melting points of the alkali metals are unusually low for metals and decrease going down the group, while the density increases going down the group with the exception of potassium (Table 1).
Table 1: Properties of the alkali metals
24.1K
Extraction: Advanced Methods00:56

Extraction: Advanced Methods

1.1K
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The V6R/V4R Index: A Novel ECG Parameter for Identifying Idiopathic Ventricular Arrhythmias Originating From the Aortic Cusp.

Journal of cardiovascular electrophysiology·2026
Same author

Spontaneous coronary artery dissection with concomitant vasospastic angina and false lumen enlargement: a case report.

European heart journal. Case reports·2026
Same author

Evaluating the Precision of Intra-Spline Bipolar Potentials With Pentaspline Pulsed Field Ablation Catheter.

Journal of arrhythmia·2026
Same author

Efficacy of Low-Voltage Area Ablation Across Substrate Size in Persistent Atrial Fibrillation: A Post Hoc Analysis of the SUPPRESS-AF Randomized Trial.

Journal of the American Heart Association·2026
Same author

Supravalvular catheter ablation of idiopathic ventricular tachycardia arising from the mitral annulus: a case report.

European heart journal. Case reports·2026
Same author

Active Fixation Quadripolar Left Ventricular Leads in Cardiac Resynchronization Therapy: Clinical Utility at Mid-Term Follow-Up.

Journal of cardiovascular electrophysiology·2026

Related Experiment Video

Updated: Jan 10, 2026

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
05:35

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography

Published on: January 17, 2020

7.9K

The Japanese Lead Extraction Registry (J-LEX): Annual Report in 2024.

Masahiko Goya1, Morio Shoda2, Kengo Kusano3

  • 1Department of Cardiovascular Medicine International University of Health and Welfare Mita Hospital Tokyo Japan.

Journal of Arrhythmia
|November 26, 2025
PubMed
Summary

The Japanese lead extraction registry (J-LEX) tracked over 5400 transvenous lead extractions (TLE) since 2018. TLE demonstrated high success rates (97.3%) with low complication rates (4.8%), primarily for infection indications.

Keywords:
complicationimplantable cardioverter defibrillatorlead extractionpacemakerprospective nationwide registry

More Related Videos

Clean Sampling and Analysis of River and Estuarine Waters for Trace Metal Studies
10:44

Clean Sampling and Analysis of River and Estuarine Waters for Trace Metal Studies

Published on: July 1, 2016

11.9K
Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
04:53

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks

Published on: May 26, 2023

1.6K

Related Experiment Videos

Last Updated: Jan 10, 2026

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
05:35

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography

Published on: January 17, 2020

7.9K
Clean Sampling and Analysis of River and Estuarine Waters for Trace Metal Studies
10:44

Clean Sampling and Analysis of River and Estuarine Waters for Trace Metal Studies

Published on: July 1, 2016

11.9K
Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
04:53

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks

Published on: May 26, 2023

1.6K

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Device Technology

Background:

  • The Japanese Heart Rhythm Society initiated the Japanese lead extraction registry (J-LEX) in 2018.
  • J-LEX is a mandatory, multi-center, prospective, observational registry for transvenous lead extraction (TLE).
  • As of end-2024, approximately 5400 TLE cases were registered across 140 centers.

Purpose of the Study:

  • To analyze the characteristics and outcomes of transvenous lead extraction procedures in Japan.
  • To evaluate the indications, procedural success, and complication rates of TLE.
  • To provide real-world data on TLE practices and patient management.

Main Methods:

  • Inclusion of all consecutive transvenous extractions, excluding surgical-only cases.
  • Data collection on patient demographics, TLE indications, procedural settings, lead characteristics, and outcomes.
  • Analysis of complete removal rates, clinical success, and perioperative complications.

Main Results:

  • Infection was the primary indication for TLE (54.5%), with high guideline classifications (Class I: 59.8%, Class IIa: 21.8%).
  • Non-infectious indications included abandoned leads, lead failure, device upgrades, and lead-related issues.
  • Complete lead removal was achieved in 96.7%, with a 97.3% clinical success rate and 4.8% perioperative complications.

Conclusions:

  • Transvenous lead extraction in Japan, as captured by the J-LEX registry, is a safe and effective procedure.
  • The registry provides valuable insights into TLE indications and outcomes, supporting evidence-based practice.
  • Continued data collection will further elucidate long-term trends and optimize TLE management.