Related Experiment Video
Updated: Jan 10, 2026

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
Published on: September 20, 2024
Advancing precision medicine in axial spondyloarthritis: insights from multi-omics approaches
Yuanpiao Ni1,2,3, Quanbo Zhang1,4, Xin Wu5
1Research Center of Hyperuricemia and Gout, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Abstract:
Axial Spondyloarthritis (axSpA) is a chronic inflammatory disease influenced by genetic, immune, metabolic, and environmental factors, significantly impacting patients' quality of life. Recent advancements in multi-omics technologies-such as genomics, transcriptomics, proteomics, and metabolomics-provide new insights into axSpA pathogenesis and precision medicine. These technologies reveal genetic susceptibility, immune responses, and metabolic alterations, uncovering potential biomarkers and therapeutic targets. This review explores multi-omics applications in understanding axSpA mechanisms, developing targeted therapies, and advancing precision diagnostics. It also addresses challenges in data integration and highlights the role of artificial intelligence (AI) in enhancing analysis precision and constructing dynamic disease networks. Combining AI with multi-omics could revolutionize diagnosis, personalized treatment, and clinical translation for axSpA, driving the future of precision medicine.
Related Concept Videos
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Genomics
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The JAK-STAT Signaling Pathway

