Related Experiment Video
Updated: Jan 10, 2026
12:18
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
7.9K
Patient Preferences for Dementia Interventions: A Scoping Review With a Systematic Review of Medications and
Ravi Gupta1,2, Shanshan Lin1, Michael J DiStefano3
1Division of General Internal Medicine, Johns Hopkin School of Medicine, Baltimore, Maryland, USA.
Journal of the American Geriatrics Society
|November 26, 2025
Summary
Understanding patient preferences for Alzheimer's disease and related dementias (ADRD) treatments is crucial. Research shows patients value memory improvement and support, but more data is needed, especially for medications.
Area of Science:
- Gerontology
- Neuroscience
- Health Services Research
Background:
- Emerging treatments for Alzheimer's disease and related dementias (ADRD) exist.
- Patient preferences for ADRD care and treatment are not well understood.
Purpose of the Study:
- To review and synthesize existing literature on patient preferences for dementia treatment and care interventions.
- To identify gaps in understanding patient preferences, particularly regarding medications.
Main Methods:
- Systematic literature search of PubMed, PsycINFO, CINAHL, and EMBASE up to November 12, 2024.
- Synthesis of findings from studies using choice-based preference elicitation and medication preference assessments.
- Included 82 studies published between 1996 and 2024, evaluating primarily non-pharmacological interventions.
Main Results:
- Patients with cognitive impairment highly value memory improvement and emotional/social support.
- Most studies focused on non-pharmacological interventions, with limited research on medication preferences.
- Data on patient preferences were heterogeneous across the included studies.
Conclusions:
- Significant gaps exist in the literature regarding treatment preferences, especially for medications, in older adults with cognitive impairment.
- Further research is needed to develop validated clinical tools for preference elicitation.
- Aligning interventions with patient values requires better methods for understanding and incorporating preferences.
More Related Videos
08:36The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living
Published on: July 28, 2022
4.3K
06:16Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
Published on: June 6, 2020
4.2K
Related Concept Videos
01:22Alzheimer's Disease: Treatment
772
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
772
01:29Nursing Interventions II: Selecting and Classifying the Nursing Interventions
3.0K
Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
3.0K
01:15Drug Dosing: Geriatric Patients
214
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
214
01:28Drug Therapy
235
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
235
01:27Pharmacodynamics in Geriatric Patients: Effects of Age
180
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
180
01:24Parkinson's Disease: Treatment
953
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
953