MoPSeq-DB: a user-friendly web application for genomic data management and analysis of marine mollusc pathogens

Sequencing technologies continue to evolve, providing novel opportunities for disease surveillance and control. These advancements are crucial for diagnosing diseases and identifying genetically distinct variants with diverse host reservoir species and geographical distributions. Recent progress in sequencing-based analyses of marine mollusc diseases has been significant, yet challenges remain in data management due to a lack of dedicated tools and databases. To address this, we present MoPSeq-DB (Mollusc Pathogen Sequences DataBase), an open-source web application for managing curated genomic data on mollusc pathogens. Designed for accessibility to non-bioinformaticians, MoPSeq-DB features interactive data visualization and integrated analysis tools. Built with the Python Django framework, it automates common bioinformatics workflows, enabling rapid exploration of sequencing data. The application has minimal hardware requirements, and is easy to install, host, and update. MoPSeq-DB facilitates systematic storage and flexible management of genomic data and metadata, improving data organization for mollusc pathogen research. Although developed with a focus on mollusc pathogens, the platform's adaptable design makes it a valuable resource for studying a wide range of pathogens. Database URL: https://mopseq-db.ifremer.fr.