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Asparaginase Hypersensitivity Reactions in NK/T-Cell Lymphomas

Javier Varela Gonzalez-Aller1, Pablo Nadal1, Salome Cañizares1

  • 1Pharmacy Department, Catalan Institute of Oncology, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.

Clinics and Practice
|November 26, 2025
PubMed
Summary

Asparaginase (ASP) chemotherapy improves outcomes in EBV-positive NK/T-cell lymphomas (NKTCL) but can cause hypersensitivity reactions (HSRs). Managing these ASP-related HSRs is crucial for patient safety and treatment effectiveness.

Keywords:
NK/T-cell lymphomaPEG-asparaginaseasparaginasecrisantaspasedrug allergyhypersensitivityneutralizing antibodies

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