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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Related Experiment Video

Updated: Jan 10, 2026

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
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Precision Oncology: Current Landscape, Emerging Trends, Challenges, and Future Perspectives.

Diane Qiao1, Richard C Wang2, Zhixiang Wang3

  • 1Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.

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|November 26, 2025
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Summary

Precision oncology tailors cancer care to individual patients using genetics and molecular profiles. This review explores its history, emerging technologies, and future directions for personalized cancer treatment.

Keywords:
cancer initiationliquid biopsymultiomicsprecision medicineprecision oncologysingle-cell spatial omicsstratificationsubtypingtargeted therapytumor heterogeneitytumor microenvironment

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Area of Science:

  • Oncology
  • Genomics
  • Personalized Medicine

Background:

  • Precision oncology, a key part of precision medicine, uses patient-specific genetic and molecular data for cancer care.
  • It has evolved to integrate advanced technologies like big data, multiomics, and liquid biopsies.
  • Understanding cancer biology, including driver genes and tumor microenvironment, is crucial.

Purpose of the Study:

  • To review the history and development of precision oncology.
  • To explore emerging technologies and novel concepts in the field.
  • To discuss molecular cancer stratification and clinical applications.

Main Methods:

  • Literature review focusing on precision oncology advancements.
  • Analysis of technological integration (big data, multiomics, liquid biopsy, CRISPR).
  • Examination of cancer biology insights (driver genes, heterogeneity, microenvironment).

Main Results:

  • Precision oncology encompasses prevention, diagnosis, and treatment tailored to individual profiles.
  • The field integrates diverse technologies and biological insights for cancer stratification.
  • Clinical applications include early detection, targeted therapy, and monitoring minimal residual disease.

Conclusions:

  • Precision oncology is rapidly advancing but faces implementation challenges.
  • Future directions involve leveraging new technologies and deeper biological understanding.
  • Successful implementation requires addressing challenges in cost, policy, and clinical integration.