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Updated: Jan 10, 2026
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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
833
Precision Oncology: Current Landscape, Emerging Trends, Challenges, and Future Perspectives.
Diane Qiao1, Richard C Wang2, Zhixiang Wang3
1Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Cells
|November 26, 2025
Summary
Precision oncology tailors cancer care to individual patients using genetics and molecular profiles. This review explores its history, emerging technologies, and future directions for personalized cancer treatment.
Area of Science:
- Oncology
- Genomics
- Personalized Medicine
Background:
- Precision oncology, a key part of precision medicine, uses patient-specific genetic and molecular data for cancer care.
- It has evolved to integrate advanced technologies like big data, multiomics, and liquid biopsies.
- Understanding cancer biology, including driver genes and tumor microenvironment, is crucial.
Purpose of the Study:
- To review the history and development of precision oncology.
- To explore emerging technologies and novel concepts in the field.
- To discuss molecular cancer stratification and clinical applications.
Main Methods:
- Literature review focusing on precision oncology advancements.
- Analysis of technological integration (big data, multiomics, liquid biopsy, CRISPR).
- Examination of cancer biology insights (driver genes, heterogeneity, microenvironment).
Main Results:
- Precision oncology encompasses prevention, diagnosis, and treatment tailored to individual profiles.
- The field integrates diverse technologies and biological insights for cancer stratification.
- Clinical applications include early detection, targeted therapy, and monitoring minimal residual disease.
Conclusions:
- Precision oncology is rapidly advancing but faces implementation challenges.
- Future directions involve leveraging new technologies and deeper biological understanding.
- Successful implementation requires addressing challenges in cost, policy, and clinical integration.
Keywords:
cancer initiationliquid biopsymultiomicsprecision medicineprecision oncologysingle-cell spatial omicsstratificationsubtypingtargeted therapytumor heterogeneitytumor microenvironmentMore Related Videos
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