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Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Related Experiment Video

Updated: May 11, 2026

A Method for Murine Islet Isolation and Subcapsular Kidney Transplantation

A Method for Murine Islet Isolation and Subcapsular Kidney Transplantation

Published on: April 13, 2011

Editorial for Special Issue "Islet Transplantation".

Shinichi Matsumoto^1,2

¹Graduate School of Medicine, Kobe University, Kobe 650-0017, Japan.

|November 26, 2025

Summary

Islet cell transplantation offers a revolutionary approach to managing type 1 diabetes. This innovative therapy aims to restore natural insulin production, improving glycemic control for patients.

Area of Science:

Endocrinology and Metabolic Diseases
Regenerative Medicine

Background:

Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-producing beta cells in the pancreatic islets.

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Last Updated: May 11, 2026

A Method for Murine Islet Isolation and Subcapsular Kidney Transplantation

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Published on: April 13, 2011

A Method for Islet Transplantation to the Omentum in Mouse

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Inguinal Subcutaneous White Adipose Tissue ISWAT Transplantation Model of Murine Islets

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Current management relies on exogenous insulin therapy, which often fails to achieve optimal glycemic control and is associated with long-term complications.