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Artificial Intelligence in Cardiac Electrophysiology: A Comprehensive Review
Pietro Cipollone1, Nicola Pierucci1, Andrea Matteucci2
1Department of Cardiovascular, Respiratory, Nephrological, Aenesthesiological and Geriatric Sciences "Sapienza", University of Rome, 00161 Rome, Italy.
Artificial intelligence (AI) enhances cardiac electrophysiology by improving arrhythmia detection and catheter ablation procedures. While AI offers diagnostic and procedural benefits, challenges in data security and ethics must be addressed for widespread clinical adoption.
Area of Science:
- Cardiology
- Medical Technology
- Artificial Intelligence
Background:
- Artificial Intelligence (AI) is increasingly integrated into cardiology, particularly electrophysiology.
- AI's capacity for analyzing complex datasets is transforming diagnostic and therapeutic strategies.
- Electrophysiology is rapidly adopting AI for enhanced patient care.
Purpose of the Study:
- To provide a comprehensive review of AI models and applications in cardiac electrophysiology.
- To examine AI's role in ECG interpretation, arrhythmia detection, atrial mapping, and catheter ablation.
- To explore the limitations and future potential of AI in electrophysiology.
Main Methods:
- Review of relevant literature on AI, Machine Learning (ML), and Deep Learning (DL) in electrophysiology.
- Thematic examination of key clinical applications of AI.
- Narrative synthesis of current AI capabilities, technologies, and outcomes in electrophysiology.
Main Results:
- AI tools effectively identify various arrhythmias, including atrial fibrillation (AF), atrial flutter (AFL), ventricular tachycardias (VTs), and long QT syndrome (LQTS).
- AI improves electro-anatomical mapping, reduces operative times, and aids in post-ablation management.
- AI demonstrates significant potential in enhancing diagnostic accuracy and procedural efficiency.
Conclusions:
- AI presents significant advantages in diagnosing arrhythmias and improving procedural efficiency in electrophysiology.
- Challenges such as data security, ethical transparency, and clinical adoption need to be addressed.
- Overcoming these limitations is key to integrating AI into routine electrophysiology practice and maximizing its future impact.
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Electrocardiogram Fundamentals
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...

