Breaking the cycle: Systematic review of perinatal interventions for parents at risk of child removal

Esther Ariyo1, Victoria Awortwe2, Ebenezer Cudjoe3

  • 1School of Health and Social Care, University of Essex, Colchester, United Kingdom.

Plos One
|November 26, 2025
PubMed

Insights

Perinatal interventions, particularly trauma-informed and relationship-based programs, show promise in preventing infant removals. Key facilitators include continuity of care and tailored support, though research limitations persist.

Area of Science:

  • Child Welfare
  • Maternal and Child Health
  • Public Health Policy

Background:

  • Infant removal from parental care is a significant child protection concern.
  • Perinatal interventions aim to support at-risk families during pregnancy to prevent child welfare involvement.
  • Evidence on the effectiveness of these early interventions requires systematic evaluation.

Purpose of the Study:

  • To systematically review the effectiveness of perinatal interventions designed to prevent infant removals.
  • To identify key service features, implementation barriers, and enablers for such interventions.

Main Methods:

  • Systematic review of peer-reviewed studies published between 2014 and 2024, sourced from electronic databases and relevant websites.
  • Inclusion criteria focused on interventions targeting pregnant parents at risk of infant removal, with outcomes related to infant removal.
  • Risk of bias assessed using the Mixed Methods Appraisal Tool (MMAT).

Main Results:

  • Six studies evaluating eight interventions met inclusion criteria, involving 3,254 pregnant women.
  • Two comparative studies suggested targeted perinatal interventions may reduce infant removals.
  • Trauma-informed, relationship-based, and multidisciplinary approaches during pregnancy were associated with reduced removals and improved maternal outcomes.

Conclusions:

  • Perinatal interventions, especially those offering holistic, relationship-based support, show potential for preventing infant removals.
  • Successful implementation hinges on continuity of care, culturally safe practices, and flexible, family-centered services.
  • The evidence base is limited by small sample sizes and methodological weaknesses, necessitating more robust, long-term research.