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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Carrying Life While Carrying Loss: Grief, PTSD, and Depression in Subsequent Pregnancy
Paulina Van1,2
1University of California, San Francisco, CA, USA.
Background: Pregnancy loss is a profoundly traumatic event that can leave lasting emotional and psychological effects. While subsequent pregnancies are often thought to ease grief, many women continue to experience unresolved distress. Objective: This pilot study examined demographic, reproductive, and psychosocial correlates of grief intensity after pregnancy loss among women in the third trimester of a subsequent pregnancy. Methods: Twenty partnered women who had experienced a prior pregnancy loss, now beyond the gestational age of that loss, were recruited from childbirth classes. Participants completed standardized measures of grief, social support, spirituality, post-traumatic stress, and depression. Results: Grief intensity was significantly related to education, gestational age at loss, perceived social support, and symptoms of post-traumatic stress and depression. Conclusions: Findings suggest that while subsequent pregnancies may soften grief, they have limited impact on PTSD and depressive symptoms. Targeted interventions remain critical for healing.
Background: Pregnancy loss is a profoundly traumatic event that can leave lasting emotional and psychological effects. While subsequent pregnancies are often thought to ease grief, many women continue to experience unresolved distress. Objective: This pilot study examined demographic, reproductive, and psychosocial correlates of grief intensity after pregnancy loss among women in the third trimester of a subsequent pregnancy. Methods: Twenty partnered women who had experienced a prior pregnancy loss, now beyond the gestational age of that loss, were recruited from childbirth classes. Participants completed standardized measures of grief, social support, spirituality, post-traumatic stress, and depression. Results: Grief intensity was significantly related to education, gestational age at loss, perceived social support, and symptoms of post-traumatic stress and depression. Conclusions: Findings suggest that while subsequent pregnancies may soften grief, they have limited impact on PTSD and depressive symptoms. Targeted interventions remain critical for healing.
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