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ERBB4 colocalizes with phosphorylated tau aggregates in multiple tauopathies

Chihiro Matsumoto1, Tomohiro Kabuta2, Terunori Sano3

  • 1Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan; Department of NCNP Brain Physiology and Pathology, Institute of Science Tokyo, Tokyo, Japan.

Neurochemistry International
|November 26, 2025
PubMed
Summary

The neuregulin-ERBB4 pathway protein ERBB4 is found in tau tangles in tauopathies like Alzheimer's disease. ERBB4 interacts with tau, suggesting a role in these neurodegenerative diseases.

Keywords:
ColocalizationERBB4Tauopathyp-tau

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