Related Experiment Video

Updated: Jan 10, 2026

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice
07:14

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice

Published on: May 23, 2025

1.5K

The Leptomeningeal Microenvironment in Metastasis: A Unique Central Nervous System Niche

Gabriele Gaggero1

  • 1Pathology Unit, IRCCS Istituto Giannina Gaslini, Genova, Italy.

Annals of Indian Academy of Neurology
|November 26, 2025
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography
09:53

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography

Published on: August 16, 2020

7.6K
Coculture System with an Organotypic Brain Slice and 3D Spheroid of Carcinoma Cells
07:48

Coculture System with an Organotypic Brain Slice and 3D Spheroid of Carcinoma Cells

Published on: October 9, 2013

21.3K

Related Experiment Videos

Last Updated: Jan 10, 2026

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice
07:14

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice

Published on: May 23, 2025

1.5K
Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography
09:53

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography

Published on: August 16, 2020

7.6K
Coculture System with an Organotypic Brain Slice and 3D Spheroid of Carcinoma Cells
07:48

Coculture System with an Organotypic Brain Slice and 3D Spheroid of Carcinoma Cells

Published on: October 9, 2013

21.3K

Related Concept Videos

The Tumor Microenvironment02:17

The Tumor Microenvironment

7.6K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
7.6K
Metastasis02:30

Metastasis

6.3K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
6.3K

Articles linked to this work by shared authors, journal, and citation graph.

An Unusual Case of Sudden Cardiac Death due to Right Coronary Artery Anomaly During the Valsalva Manoeuvre: A Case Report and Literature Review.

Academic forensic pathology·2026

Corrigendum to "Redefining ultrasound's role in early diagnosis of hepatosplenic candidiasis during neutropenia: A pediatric case report in solid tumor" [Med. Mycol. Case Rep., 51 (2026) 100777].

Medical mycology case reports·2026

Sialic Acids in Kidney Disease: Immune Regulation, Complement Activation and Glomerular Injury.

Antioxidants (Basel, Switzerland)·2026

Clinical Significance of Renal Tissue in Neonatal Sacrococcygeal Teratoma: A Case Report With Review of Literature.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·2026

Very rapid response to belzutifan of VHL-related intracranial and retinal hemangioblastomas.

American journal of ophthalmology case reports·2026

Tumor Microenvironment and Immune Response Against Wilms Tumor: Evasion Mechanisms and Implications for Immunotherapeutic Approaches.

Cancers·2026

Malnutrition in Females and Anxiety in Males Predicts Mild Neurocognitive Disorder: Insights from LASI-DAD.

Annals of Indian Academy of Neurology·2026

Electrophysiological Profile and Comparative Analysis in Brachial Plexus Injuries.

Annals of Indian Academy of Neurology·2026

Undetected Cognitive Impairment in Saudi Arabia: A National Analysis of Screening Coverage, Diagnostic Yield, and Equity Gaps in Primary Healthcare.

Annals of Indian Academy of Neurology·2026

Speech-Induced Myoclonus-Dystonia Mimicking Stuttering and Responding to Zonisamide.

Annals of Indian Academy of Neurology·2026

A Retrospective, Single-Arm, Observational Study in Patients with Multiple Sclerosis in India Receiving Ocrelizumab Therapy for 1 Year.

Annals of Indian Academy of Neurology·2026

Knowledge and Attitude Related to Stroke and Factors Associated with them Among Adults Aged 18 Years and Above in Kerala, India: A Community-Based Cross-Sectional Study.

Annals of Indian Academy of Neurology·2026

Trastuzumab Deruxtecan-Associated Pneumonitis in Non-Breast Solid Tumors: A Retrospective Cohort Study.

Journal of immunotherapy and precision oncology·2026

Radiation Monotherapy for Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type: A Case Report.

Cureus·2026

A prospective clinical study to understand the factors affecting healing of intestinal primary repair and anastomosis at a tertiary care centre.

Bioinformation·2026

Liver transplantation for pediatric liver tumors: a case report of hepatic angiosarcoma with literature review.

Quantitative imaging in medicine and surgery·2026

Clinical presentation and epidemiological patterns of breast lesions: Experience from a tertiary care hospital.

Bioinformation·2026

Potential utilization of lymphoscintigraphy in patients with kaposiform hemangioendothelioma.

Quantitative imaging in medicine and surgery·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us