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Early Favourable Outcomes of Valve Repair in Congenital Heart Surgery

Muhammed Ikbal Aydin1, Eiri Kisamori2, Mitchell Haverty1

  • 1Department of Cardiovascular Surgery, Children's National Hospital, Washington, DC, 20010, United States.

Interdisciplinary Cardiovascular and Thoracic Surgery
|November 26, 2025
PubMed

Insights

Pediatric valve repair for congenital heart disease shows reliable early survival and freedom from reoperation. However, single ventricle patients face higher mortality risks, especially when undergoing surgery at a younger age.

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Surgery
  • Valvular Heart Disease

Background:

  • Mechanical valve replacement is common in pediatric valvular heart surgery.
  • Optimal long-term survival may necessitate a shift towards valve repair.
  • Current practices in valve repair for congenital heart disease require analysis.

Purpose of the Study:

  • To review current practices in valve repair for congenital heart disease.
  • To analyze the outcomes of valve repair in pediatric patients.
  • To identify risk factors associated with mortality after valve repair.

Main Methods:

  • Retrospective analysis of 90 pediatric patients (30 semilunar, 60 atrioventricular valves) undergoing valve repair.
  • Kaplan-Meier analysis for survival and freedom from reoperation.
  • Cox regression to assess risk factors for mortality, including single ventricle physiology and age at surgery.

Main Results:

  • Estimated 12-month survival was 95.2% for semilunar and 95% for AV valves.
  • Estimated 12-month freedom from reoperation was 95.8% for semilunar and 95.6% for AV valves.
  • Single ventricle morphology and younger age at surgery were significant risk factors for mortality.

Conclusions:

  • Valve repair in congenital heart disease offers reliable early outcomes in a complex pediatric population.
  • Patients with single ventricle physiology undergoing early surgery face the highest risk of adverse outcomes.
  • Further research into optimizing repair strategies for high-risk groups is warranted.
Abstract

Keywords:
atrioventricular valvecongenital valve repairsemilunar valve

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