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Scoping review for treatment of osteolysis in total ankle arthroplasty
Angela Seidel1,2, Michael Li3,4, Karl-Andre Lalonde3
1Division of Orthopedic Surgery, The Ottawa Hospital, University of Ottawa, 1053 Carling Avenue, Ottawa, ON, K1Y 4E9, Canada. Angela.seidel@h-fr.ch.
Background:
Following total ankle replacement (TAR), osteolysis is a known complication. No consensus exists regarding management.
Methods:
Applying the Arksey and O'Malley framework for scoping studies, a study protocol and a data extraction form was created. The research included all studies until March 2025. Study selection and data extraction were performed by two independent reviewers.
Results:
Two hundred and eighty-seven studies were identified, of which 54 studies (case series and case reports) were included. 69% of the studies included below 10 cases. The most common reported treatment was bone grafting in n = 36 (67%) of studies. The conversion of the TAR to an ankle fusion (n = 16 studies, 30%) was more frequent than the revision to a TAR (n = 15 studies, 28%). Eleven studies reported multiple treatment options. Long-term follow-up and standardized outcome measurements were infrequently discussed.
Conclusion:
This scoping review demonstrates that the existing literature is highly heterogeneous and insufficient to recommend standard treatment.
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