Indicators of early transfusion in paediatric trauma: a retrospective analysis of 11,849 cases from the TraumaRegister DGU®
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View abstract on PubMed
Summary
This summary is machine-generated.This study identified key indicators for early red blood cell (RBC) transfusions in pediatric trauma patients. Polytrauma, penetrating injuries, and abdominal trauma significantly increase the need for RBC transfusions.
Area Of Science
- Trauma Management
- Pediatric Critical Care
- Hemorrhage Control
Background
- Red blood cell (RBC) transfusion is an emerging strategy in pediatric trauma care, including prehospital settings.
- Current parameters for predicting transfusion needs in children are insufficient.
- This study sought to identify early indicators for RBC transfusions in pediatric trauma patients.
Purpose Of The Study
- To identify predictive parameters for early in-hospital red blood cell (RBC) transfusions in pediatric trauma patients.
- To assess the utility of prehospital and early in-hospital parameters for predicting transfusion needs.
- To develop a predictive model for RBC transfusion requirements in pediatric trauma.
Main Methods
- Retrospective analysis of the German TraumaRegister DGU® (15-year period).
- Inclusion of children and adolescents aged 1-16 years.
- Multivariate regression analysis to identify risk factors and receiver operating characteristic (ROC) curve analysis to evaluate predictive capacity.
Main Results
- Out of 11,849 patients, 5.9% received RBC transfusions.
- Polytrauma, penetrating, and abdominal injuries were associated with the highest risk of transfusion.
- Cardiopulmonary resuscitation, endotracheal intubation, and Glasgow Coma Scale (GCS) ≤ 8 were significant predictors.
- A predictive model achieved an area under the ROC curve (AUC) of 0.87; prehospital parameters yielded an AUC of 0.80.
Conclusions
- Polytrauma, abdominal and penetrating injuries, GCS ≤ 8, tracheal intubation, and cardiopulmonary resuscitation increase the likelihood of RBC transfusion.
- Identified risk factors aid in recognizing pediatric trauma patients at risk for severe hemorrhage and transfusion.
- The developed model offers valuable insights for timely transfusion decisions in pediatric trauma management.
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